Discover and Validate the Right Target for the Right Patients
BullFrog Data Networks® incorporate publicly available, proprietary, and/or custom data sources to generate novel insights toward target identification and validation, understanding mechanism of action, clinical trial optimization, drug repurposing, and more. Data Networks can be created for any therapeutic area, and we use this technology in our own R&D pipeline including in oncology and CNS indications.
Applications for Discovery and Development
Our approach finds patient subgroups with similar molecular signatures and identifies the most relevant genes driving disease biology. Data Networks created from this process generate insights that allow researchers to accelerate drug discovery and development and increase the odds of technical and regulatory success.
- Target Identification and Validation: Cluster similar patients based on multi-omics data, identifying those patients that have the same molecular subtype, and identify which genes are responsible for disease biology.
- Clinical Trial Optimization: Identify predictive endpoints, biomarkers, and high-responder patient populations using past and public trial data sets to optimize clinical trials for safety and efficacy.
Watch video below for examples in oncology target discovery:
